Science & Research

Our published research and research initiatives can be found below.

Our Team’s Published Research

N-acetylcysteine and Its Immunomodulatory Properties in Humans and Domesticated Animals

Immunoceuticals: Harnessing Their Immunomodulatory Potential to Promote Health and Wellness

Beyond the Coagulation Cascade: Vitamin K and Its Multifaceted Impact on Human and Domesticated Animal Health

Variation in ovine serum vitamin D concentrations from late summer to early spring and during immune challenge with bacterial endotoxin

Vitamin D Influences the Activity of Mast Cells in Allergic Manifestations and Potentiates Their Effector Functions against Pathogens

More Vitamin D Articles

Vitamin D Supplementation and Incident Dementia: Effects of Sex, APOE, and Baseline Cognitive Status

Vitamin D and Risk for Type 2 Diabetes in People with Prediabetes: A Systematic Review and Meta-Analysis of Individual Participant Data from 3 Randomized Clinical Trials

Vitamin D Supplementation Increases Objective Response Rate and Prolongs Progression-Free Time in Patients with Advanced Melanoma Undergoing Anti-PD-1 Therapy

Vitamin D Influences the Activity of Mast Cells in Allergic Manifestations and Potentiates Their Effector Functions against Pathogens

Videos on Vitamin D3 and K2

The Benefits of Vitamin K2 - Dr. Pradip Jamnadas, Cardiologist

The Benefits of Vitamin D and K2 - Dr. John Campbell, PhD

Vitamin D and Dementia - Dr. John Campbell, PhD

Vitamin D

Vitamin D and Ageing

Increased Risk of Vitamin D Deficiency among HIV-Infected Individuals : A Systematic Review and Meta-Analysis

Association of Vitamin D Deficiency with Pulmonary Tuberculosis: A Systemic Review and Meta-Analysis

The Crosstalk between Vitamin D and Pediatric Digestive Disorders

Biophysical Evidence to Support and Extend the Vitamin D-Folate Hypothesis as a Paradigm for the Evolution of Human Skin Pigmentation

Genetic Determinants of 25-Hydroxyvitamin D Concentrations and their Relevance to Public Health

Vitamin D – The Sunshine Vitamin

Vitamin D Deficiency in Elderly People in Swedish Nursing Homes is Associated with Increased Mortality

The Synergistic Interplay Between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review

Is Vitamin D Deficiency a Major Global Health Problem?

Evaluation, Treatment, and Prevention of Vitamin D Deficiency: An Endocrine Society Clinical Practice Guideline

The Vitamin D Deficiency Pandemic: Approaches for Diagnosis, Treatment, and Prevention

25-Hydroxyvitamin D and Risk of Myocardial Infarction in Men: A Prospective Study

Vitamin D-Insufficiency: An Estimate of the Situation in Germany

Immunologic Effects of Vitamin D on Human Health and Disease

Vitamin D and the Immune System

Emerging Role of Vitamin D in Autoimmune Diseases: An Update on Evidence and Therapeutic Implications

Randomized Trial of Vitamin D Supplementation to Prevent Seasonal Influenza A in Schoolchildren

Vitamin D and Influenza – Prevention or Therapy?

Tuberculosis: A Global Health Problem

Vitamin D and the Risk of Latent Tuberculosis Infection: A Systematic Review and Meta-Analysis

18th Century Sanatoria Revisited: Sunlight and Health

25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2

Pre-infection 25-Hydroxyvitamin D3 Levels and Association with Severity of COVID-19 Illness

Vitamin D Sufficiency, a Serum 25-Hydroxyvitamin D at Least 30 ng/mL Reduced Risk for Adverse Clinical Outcomes in Patients with COVID-19 Infection

Effect of Calcifediol Treatment and Best Available Therapy Versus Best Available Therapy on Intensive Care Unit Admission and Mortality Among Patients Hospitalized for COVID-19: A Pilot Randomized Clinical Study

Effects of a 2-Week 5000 IU Versus 1000 IU Vitamin D3 Supplementation on Recovery of Symptoms in Patients with Mild to Moderate Covid-19: A Randomized Clinical Trial

Effect of a Single High Dose of Vitamin D3 on Cytokines, Chemokines, and Growth Factor in Patients with Moderate to Severe COVID-19

Meta-Analyses Support the Use of Vitamin D

Factors Influencing Vitamin D Status

Vitamin D Deficiency in a Healthy Group of Mothers and Newborn Infants

The Vitamin D Deficiency Pandemic: Approaches for Diagnosis, Treatment, and Prevention

Vitamin D Deficiency in Elderly People in Swedish Nursing Homes is Associated with Increased Mortality

Vitamin D Toxicity - A Clinical Perspective

Cohort Study to Evaluate the Effect of Vitamin D, Magnesium, and Vitamin B12 in Combination on Progression to Severe Outcomes in Older Patients with Coronavirus (COVID-19)

Why Supplement with Vitamin K

The Occurrence and Chemical Nature of Vitamin K

Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities

Vitamin K - Sources, Physiological Role, Kinetics, Deficiency, Detection, Therapeutic Use, and Toxicity

Vitamin K and Rheumatoid Arthritis

Dietary Reference Intakes Tables: Reference Values for Vitamins

Vitamin K-Containing Dietary Supplements: Comparison of Synthetic Vitamin K and Natto-Derived Menaquinone-7

Effect of Low-Dose Supplements of Menaquinone-7 (Vitamin K2) on the Stability of Oral Anticoagulant Treatment: Dose Response Relationship in Healthy Volunteers

US Pharmacopeial Convention Safety Evaluation of Menaquinone-7, a Form of Vitamin K

Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health

Identification of UBIAD1 as a Novel Human Menaquinone-4 Biosynthetic Enzyme

Vitamin K - Sources, Physiological Role, Kinetics, Deficiency, Detection, Therapeutic Use, and Toxicity

The Role of Menaquinones (Vitamin K2) in Human Health

Comparison of Menaquinone-4 and Menaquinone-7 Bioavailability in Healthy Women

Government of Canada, Statistics Canada. Leading Causes of Death in Canada

Beneficial Effects of Vitamin D and K on the Elastic Properties of the Vessel Wall in Postmenopausal Women: A Follow-Up Study

Joint Association of Low Vitamin D and Vitamin K Status with Blood Pressure and Hypertension

Vitamin K-Dependent Carboxylation of Matrix Gla Protein Influences the Risk of Calciphylaxis

Spontaneous Calcification of Arteries and Cartilage in Mice Lacking Matrix GLA Protein

Gla-Rich Protein is Involved in the Cross Talk Between Calcification and Inflammation in Osteoarthritis

Effect of Vitamin K2 (metaquinone-7) in Fermented Soybean (natto) on Bone Loss in Ovariectomized Rats

Ucmaa (Grp-2) is Required for Zebrafish Skeletal Development. Evidence for a Functional Role of its Glutamate γ-Carboxylation

Integration of the NFκB p65 Subunit into the Vitamin D Receptor Transcriptional Complex: Identification of p65 Domains that Inhibit 1,25-Dihydroxyvitamin D3 Stimulated Transcription

The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Heatlh: A Narrative Review